5.  Anker® 2.4G Wireless Vertical Ergonomic Optical Mouse, 800 / 1200 /1600DPI, 5 Buttons – Black

This vertical mouse is number five on the list. It has an ergonomic shape and is also very stylish if that matters to you. This mouse would help with shoulder and wrist pain by keeping your wrist in a upright position and forcing you to move your whole arm instead of just your wrist. Best part of this is that it’s only $23.99!

I would not recommend this mouse if you have pain in your forearm from clicking.

 About Anker
Anker offers diverse consumer tech solutions including batteries, adapters, networking devices, and more. We are passionate about excellence so that with every Anker brand purchase, you can expect to find quality materials, reliable performance, affordable prices, and great customer service.
The Anker 2.4G wireless vertical ergonomic optical mouse is designed to reduce forearm twisting and the resulting repetitive stress and pain. The vertical “handshake” position encourages a neutral wrist and arm alignment for greater comfort and better health. No finger contortions are needed to operate the easy-to-reach buttons. The thumb rest has been reshaped to provide even more comfort over earlier versions, and the addition of two navigational thumb buttons allow for smoother, faster web browsing.
Windows 8 / 7 / Vista / XP / 2000
Mac OS X(The two thumb buttons are not recognized on the Mac OS X.)Package included:
1 x Anker wireless vertical mouse (2 AAA batteries NOT included)
1 x nano receiverBuy with confidence:
Next business day shipping
24 x 7 Email Support
18 Month Warranty
Due to the innovative design of this ergonomic mouse, you may initially find it difficult to use. Please continue use over several days to grow accustomed to and enjoy the full comfort of the design.

4. Evoluent VerticalMouse 4 Right Wireless VM4RW

The fourth mouse on the list is also a vertical mouse. This mouse has six buttons and a scroll. It gives you full grip and if you have smaller hands you should check out the smaller version of it HERE.  This mouse is also good for wrist and shoulder pain.  Having a full grip also seemed to help with forearm pain.
You can check out the regular sized version on the link below:

From the Manufacturer

The patented shape supports your hand in an upright neutral posture that generally avoids forearm twisting. Many users, including medical doctors, ergonomists and physical therapists, said the Evoluent Vertical Mouse provides superior comfort and even relieved their wrist pain.

3.  Logitech M570 Wireless Trackball

 The number one trackball on Amazon.  It has a five star rating and over 4,000 reviews.
Trackballs are good for shoulder and wrist pain from mouse movement.
It will not help with pain from either clicking or mouse scrolling.
Stay-put comfort
  • Thumb-controlled trackball stays in one place
  • No need to slide around a mouse or move your arm to move your cursor
  • Sculpted shape supports your hand for comfortable control all day long
Plug-and-forget Unifying receiver
  • Wireless receiver is so tiny it can stay in your laptop
  • Add five more Unifying-compatible devices like a wireless keyboard without multiple receivers filling up your USB ports
Power to spare
  • Go for up to 18 months without a battery change
  • Uses just one AA battery (included)
  • Battery indicator light eliminates surprises

Click here to purchase on Amazon:  Logitech M570 Wireless Trackball

2. Logitech G13 Programmable Gameboard with LCD Display

Not a mouse at the number 2 spot but a great mouse helper.  You can set the side buttons near the joystick to left and right click eliminating the need to click with your right hand.  Also, can set up the macro buttons to scroll up and down allowing you to scroll fast.  This is perfect for people who have forearm and wrist pain from clicking and scrolling.  Great for games as well.  Great Logitech drivers and I recommend using this with our number one choice or another Logitech mouse.
Purchase on link below on Amazon:
logitech wireless performance mouse mx

This mouse is light and shaped very nice to fit your hands.  It has a very light click and a super scroll.  If you have pain from clicking or mouse scrolling this is the mouse to get.  You can also set the side buttons to act as a mouse click button which can also lessen the load on your clicking finger.  It has great drivers and great battery life.  Highly recommend using this with the Logitech G13 Programmable Gameboard with LCD Display.

Click below to purchase on Amazon:

Logitech Wireless Performance Mouse MX for PC and Mac